Jing zhang apple12/7/2023 ![]() ![]() Published by PNAS.Ĭharacterization of candidate genes encoding biosynthesis of major triterpenes. Our work mechanistically details the metabolic diversity that arose post-WGD and provides insights into the genomic basis of medicinal properties of loquat, which has been used in both traditional and modern medicines.Īpple tribe comparative genomics evolution polyploidy triterpene biosynthesis.Ĭopyright © 2021 the Author(s). trifoliata and loquat, which pre- and postdate the Maleae WGD, respectively. We then functionally characterize contrasting metabolic pathways responsible for major triterpene biosynthesis in G. After generating chromosome-level assemblies of a widely cultivated loquat variety and Gillenia trifoliata, we define differentially evolved, duplicated gene pathways and date the WGD in the apple tribe at 13.5 to 27.1 Mya, much more recent than previously thought. Here, we reveal how WGD laid the foundation for co-option and differentiation of medicinally important ursane triterpene pathway duplicates, generating distinct chemotypes between species and between developmental stages in the apple tribe. 6 State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops, Ministry of Agriculture and Rural Affairs, College of Horticulture, South China Agricultural University, Guangzhou 510642, China 7 Joint Center for Single Cell Biology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China duplication (WGD) plays important roles in plant evolution and function, yet little is known about how WGD underlies metabolic diversification of natural products that bear significant medicinal properties, especially in nonmodel trees.6 State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops, Ministry of Agriculture and Rural Affairs, College of Horticulture, South China Agricultural University, Guangzhou 510642, China 7 Joint Center for Single Cell Biology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China PMC article.5 Future Food Beacon and School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom.4 Joint Center for Single Cell Biology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.3 Key laboratory of Loquat Germplasm Innovation and Utilization (Fujian Province), Putian University, Putian 351100, China.2 Research Cooperation Department, Beijing Genomics Institute Genomics, Shenzhen 518083, China.1 State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops, Ministry of Agriculture and Rural Affairs, College of Horticulture, South China Agricultural University, Guangzhou 510642, China. ![]()
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |